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Tools and guides for your GLP‑1.

Free calculators built on the app’s own formulas, and plain-language guides from the labels and the trials.

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Side effects

GLP‑1 side effects, week by weekNausea, diarrhea and constipation are the most common GLP-1 side effects. They peak in the first weeks and after each dose increase, then usually ease.Nausea on a GLP‑1: why it happens and what helpsNausea hit 44% on Wegovy 2.4 mg and 25% to 29% on Zepbound in trials. It peaks after dose increases and usually eases. What helps, and when to call.Constipation on a GLP‑1: causes, fixes, red flagsConstipation hit 24% on Wegovy 2.4 mg and 11% to 17% on Zepbound in trials. Fiber added slowly, fluids and movement help. Red flags inside.Diarrhea on GLP‑1s: how long it lasts and what helpsDiarrhea hit 30% on Wegovy and 19% to 23% on Zepbound in trials, mostly during dose increases. Here is what helps and when to call.Sulfur burps, heartburn and reflux on GLP‑1sBurping hit 7% on Wegovy and 4% to 5% on Zepbound, reflux 4% to 5%. Slower stomach emptying is why. What helps, and when to get care.Fatigue on a GLP‑1, and what helpsTiredness was reported by 11% on Wegovy 2.4 mg and 5% to 7% on Zepbound, vs 3% to 5% on placebo. Eating far less, fluids and sleep often play a part.Hair loss on a GLP‑1: why it happens and what helpsHair loss was reported by about 3% on Wegovy 2.4 mg and 4% to 5% on Zepbound vs 1% on placebo. It is tied to weight loss and usually temporary.Ozempic face: what it is and what actually helps“Ozempic face” is facial volume loss after weight loss, not a listed drug side effect. One study found about 7% less midface volume per 10 kg lost.Zepbound and Mounjaro side effectsOn Zepbound, 25% to 29% had nausea vs 8% on placebo. Gut side effects peak during the 2.5 mg step-ups and ease over time. Rates, timing and red flags.Wegovy and Ozempic side effects, explainedOn Wegovy 2.4 mg, 44% of trial patients had nausea vs 16% on placebo. Gut side effects peak during dose increases and usually ease with time.

Your medication

How GLP‑1 medications work, in plain wordsGLP-1 medicines copy a gut hormone that curbs appetite, slows the stomach and helps release insulin. They last days, not minutes, so most are weekly.Your first month on a GLP‑1, week by weekThe first 4 weeks on Wegovy, Ozempic, Zepbound or Mounjaro use a starting dose. Expect appetite changes, some nausea, and modest early weight change.GLP‑1 shot day: what to expect and what to eatAfter a weekly Wegovy, Ozempic, Zepbound or Mounjaro shot, drug levels peak within about 1 to 3 days. Small, bland, protein-rich meals and fluids help.GLP‑1 injection sites and how to rotate themWegovy, Ozempic, Zepbound and Mounjaro go under the skin of the stomach, thigh or upper arm. The labels say to rotate sites with each dose.Weight-loss plateaus on a GLP‑1In trials, weight loss on semaglutide leveled off near week 60, and most people on tirzepatide plateaued by week 72. What a stall means and what helps.Semaglutide vs tirzepatide, side by sideIn the head-to-head SURMOUNT-5 trial, tirzepatide averaged 20.2% weight loss at 72 weeks vs 13.7% for semaglutide. Both mainly cause gut side effects.Wegovy vs Ozempic, Zepbound vs MounjaroWegovy and Ozempic are both semaglutide; Zepbound and Mounjaro are both tirzepatide. Each pair differs in approved use, dose ladder, top dose and pens.The Wegovy pill, explainedThe Wegovy pill is daily oral semaglutide. In its 64-week trial, the 25 mg dose averaged 13.6% weight loss vs 2.4% on placebo.Traveling with a GLP‑1 pen: storage, TSA and shot dayHow long GLP-1 pens can stay out of the fridge, what TSA allows in your carry-on, and how labels handle shot day when you travel.Coming off a GLP‑1: how to keep the weight offIn trials, most people regained a large share of lost weight within a year of stopping semaglutide or tirzepatide. Here is what helps.

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